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euphorbiafactor L2
CAS No. 218916-51-9
euphorbiafactor L2( —— )
Catalog No. M20416 CAS No. 218916-51-9
Euphorbiafactor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 171 | In Stock |
|
| 10MG | 250 | In Stock |
|
| 25MG | 422 | In Stock |
|
| 50MG | 620 | In Stock |
|
| 100MG | 885 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product Nameeuphorbiafactor L2
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NoteResearch use only, not for human use.
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Brief DescriptionEuphorbiafactor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.
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DescriptionEuphorbiafactor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetNF-κB
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RecptorNF-κB
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Research Area——
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Indication——
Chemical Information
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CAS Number218916-51-9
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Formula Weight642.7
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Molecular FormulaC38H42O9??
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (129.65 mM)
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SMILES[H][C@]12C[C@@H](OC(=O)c3ccccc3)C(=C)[C@H](OC(C)=O)[C@@]3([H])[C@@H](OC(=O)c4ccccc4)[C@@H](C)C[C@]3(OC(C)=O)C(=O)\C(C)=C/[C@@]1([H])C2(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Scopolin
Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for angiogenesis related diseases and can serve as a structural base for screening more potent synthetic analogs.
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Urolithin B
Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK.?Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
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NF-κB/MAPK-IN-1
NF-κB/MAPK-IN-1 is a potent dual inhibitor of the NF-κB and MAPK pathways with potential anti-inflammatory activity, inhibition of NO production, and inhibition of LPS-induced activation of iNOS, COX-2, ERΚ and P38.
